Connected components of significantly dysregulated metabolites.

<p>The metabolite-centric network was reconstructed from the perturbed reactions in T2DM. Insignificant enriched metabolites were removed from the network. The two biggest connected components were found. The right component mainly consists of amino acids. The left component comprises metaboli...

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Bibliographic Details
Main Author:	Maryam Khoshnejat (9294122) (author)
Other Authors:	Ali Mohammad Banaei-Moghaddam (4371640) (author), Ali Akbar Moosavi-Movahedi (313649) (author), Kaveh Kavousi (5879501) (author)
Published:	2023
Subjects:	Biochemistry Cell Biology Genetics Physiology Cancer Virology Computational Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified system biology approach personalized metabolic modeling newly diagnosed patients machine learning method blood sugar homeostasis understanding metabolism reprogramming pathways possibly interrupts muscle metabolic reprogramming specific metabolic model 13 exchange metabolites develops insulin resistance insulin resistance muscle metabolism glucose homeostasis several pathways dysfunctional metabolism major insulin discriminating insulin skeletal muscle resistant muscle human muscle signaling process sensitive tissue results indicated pivotal role mainly implicating lipids metabolisms holistic view first reconstructed extracellular matrix ecm ). early stage early diagnosis building membrane amino acids
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Connected components of significantly dysregulated metabolites.

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