Peptides and their respective concentrations evaluated for their effects in the PTZ-induced seizure model.

Peptides and their respective concentrations evaluated for their effects in the PTZ-induced seizure model.

<p>Peptides and their respective concentrations evaluated for their effects in the PTZ-induced seizure model.</p>

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Bibliographic Details
Main Author: Jhonathan Angel Araujo Fernández (21181779) (author)
Other Authors: Thatiane Cristina de Moura (21181782) (author), Sabela Fernández Vila (21181785) (author), Juan Andrés Rubiolo Gaytán (21181788) (author), Iñaki López-Díaz (21181791) (author), Soraya Learte-Aymamí (21181794) (author), M. Eugenio Vázquez (2506132) (author), Maria D. Mayán (21181797) (author), Laura Sánchez (471954) (author), Claudia Vianna Maurer-Morelli (21181800) (author)
Published: 2025
Subjects:
Physiology
Pharmacology
Biotechnology
Immunology
Cancer
Science Policy
Biological Sciences not elsewhere classified
shortened life expectancy
quantified swimming activity
measured transcript levels
increased health risks
future research aimed
elucidate underlying mechanisms
cx43derivated peptide ).
6 days post
preclinical studies play
assessed seizure frequency
developing novel anti
danio rerio </
modulate gene expression
div >< p
cx2 peptide reached
biodistribution analysis confirmed
induced seizure model
two different peptides
tripeptide exhibited anti
two peptides
induced seizures
additional studies
seizure treatments
seizure responses
seizure induction
modulating seizure
although anti
fos </
zebrafish ptz
zebrafish larvae
zebrafish brain
zebrafish (<
various concentrations
uncontrolled seizures
term efficacy
successfully employed
results indicate
remain pharmacoresistant
related pathways
recurrent seizures
genes related
findings demonstrate
experimental groups
epileptic therapies
epileptic seizures
drug discovery
direct role
cx2 peptides
crucial role
bcl2a ,</
approximately 30
apoptosis (<
24h prior
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