Composite biomaterial repair strategy to restore biomechanical function and reduce herniation risk in an ex vivo large animal model of intervertebral disc herniation with varying injury severity

Composite biomaterial repair strategy to restore biomechanical function and reduce herniation risk in an ex vivo large animal model of intervertebral disc herniation with varying injury severity

<div>Abstract: Back pain commonly arises from intervertebral disc (IVD) damage including annulus fibrosus (AF) defects and nucleus pulposus (NP) loss. Poor IVD healing motivates developing tissue engineering repair strategies. This study evaluated a composite injectable IVD biomaterial repair...

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Bibliographic Details
Main Author: Warren Hom (6199418) (author)
Other Authors: Melanie Tschopp (6199940) (author), Huizi A. Lin (6199941) (author), Philip Nasser (6199944) (author), Damien M. Laudier (354850) (author), Andrew C. Hecht (629030) (author), Steven B Nicoll (5864861) (author), James C. Iatridis (413611) (author)
Published: 2019
Subjects:
Clinical microbiology
Orthopaedics
Regenerative medicine (incl. stem cells)
Intervertebral Disc
Annulus Fibrosus
Nucleus Pulposus
Biomechanics
Discectomy Injury Models
Hydrogels
Regenerative Medicine (incl. Stem Cells and Tissue Engineering)
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