Flow chart of research design and analysis.

<div><p> Objective </p><p>This study aims to investigate and analyze the differentially expressed genes (DEGs) in CD34 + hematopoietic stem cells (HSCs) from patients with myelodysplastic syndromes (MDS) through bioinformatics analysis, with the ultimate goal of uncovering th...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Min-xiao Wang (20868922) (author)
مؤلفون آخرون:	Chang-sheng Liao (18591969) (author), Xue-qin Wei (20868925) (author), Yu-qin Xie (20868928) (author), Peng-fei Han (694841) (author), Yan-hui Yu (20868931) (author)
منشور في:	2025
الموضوعات:	Cell Biology Genetics Molecular Biology Marine Biology Infectious Diseases Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified targeted interventions directed svm )&# 8212 support vector machine may also guide hematopoietic stem cells exploring therapeutic strategies downloaded three datasets core predictive models provide new insights revealed significant differences results independently using ensure data consistency differentially expressed genes provide novel insights xlink "> initially study sheds light performed differential analysis enhance prediction accuracy clinical treatment strategies two key genes key pathogenic genes differential gene expression xlink "> key genes significant changes prediction results novel perspective gene groups data preprocessing expression levels expression analysis identify genes genes associated findings provide validation set ultimate goal training sets training set thereby integrating study aims robust list random forest pathological process particular focus notably downregulated myelodysplastic syndromes mechanisms underlying lasso regression gse19429 dataset figure illustrates enrichment analysis effective treatments disease initiation disease features disease diagnosis disease characteristics depth analysis delve deeper control group comprehensive evaluation combat algorithm bioinformatics analysis analysis workflow
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Flow chart of research design and analysis.

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