Preclinical assays survival times.

Preclinical assays survival times.

<div><p>Snakebite is a significant public health concern in Africa, with the viperid species <i><i>Echis ocellatus</i></i> being responsible for the majority of snakebite deaths in West Africa. Recently <i><i>E. ocellatus</i></i> underwent...

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Главный автор:	Rebecca J. Edge (12732488) (author)
Другие авторы:	Amy E. Marriott (10519764) (author), Molly Keen (21983146) (author), Tiffany Xie (21983149) (author), Edouard P. Crittenden (17677320) (author), Charlotte A. Dawson (17632944) (author), Mark C. Wilkinson (2202700) (author), Wolfgang Wüster (360453) (author), Nicholas R. Casewell (7062380) (author), Stuart Ainsworth (4520902) (author), Stefanie K. Menzies (9262708) (author)
Опубликовано:	2025
Предметы:	Biochemistry Cell Biology Biotechnology Ecology Cancer Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified underwent taxonomic revision first detailed analysis albeit still significant antivenom could neutralise saimr echis provided recently taxonomically partitioned questions regarding differences div >< p two redefined species murine preclinical assays echiven provided 100 specific toxin activity comparative potency assays several antivenoms raised echis ocellatus </ saimr echis two species comparative potency preclinical evaluation confer 100 antivenom doses viperid species toxin effects toxin activities comparative doses assays utilised vivo </ vitro </ str </ romani </ ocellatus </ strongest phospholipase snake skins romani ,</ recognised comparably preclinically efficacious ocellatus ,</ modest differences mitochondrial barcoding lethal effects insignificant activity findings demonstrate existing antivenoms echiven antivenoms best protection antivenoms indicated >’ envenoming >, leading
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