Impact of METTL3 and ERK2 on <i>gB</i> mRNA Levels.

<p>(A) The endogenous ERK2 distribution was detected between the Mock and PRV 18 h after infection (MOI = 0.4). (B) HeLa cells were transfected with empty vector, 3 × FLag-CMV-14-ERK2, pCAGGS-HA-METTL3, and 3 × FLag-CMV-14-ERK2 + pCAGGS-HA-METTL3, respectively. After 12 h, cells were infected...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Lucai Wang (22050158) (author)
مؤلفون آخرون:	Xiangqi Qiu (22050161) (author), Lele Wang (542468) (author), Xilong Yang (20877464) (author), Mengjie Li (141854) (author), Xuyang Zhao (1951429) (author), Wenhui Zhu (3592448) (author), Lijie Lv (18554075) (author), Yunzhe Kang (22050164) (author), Lulu Yao (4640143) (author), Gaiping Zhang (106747) (author), Aijun Sun (466105) (author), Guoqing Zhuang (9905778) (author)
منشور في:	2025
الموضوعات:	Biochemistry Microbiology Molecular Biology Immunology Science Policy Mental Health Infectious Diseases Virology Biological Sciences not elsewhere classified providing new avenues intensified organ damage suppressing viral replication herpesvirus pseudorabies virus enzymatic active site mettl3 expression decreased div >< p mettl3 axis acts study reveals phosphorylation 6 </ sup erk2 phosphorylates mettl3 mettl3 axis site enhances mediated phosphorylation vivo </ vitro </ mettl3 ’ methyltransferase mettl3 κb pathway β production work establishes translational modifications terminal domain suppressing ifn serine 43 paradigm shift overexpressing erk2 novel regulator mapk signaling immunoregulatory activity identifies ser43 herpesvirus infection hastened mortality functional hotspot dependent crosstalk combined treatment antiviral defense
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Impact of METTL3 and ERK2 on <i>gB</i> mRNA Levels.

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