Experimental verification of panGEM predictions for carbon-source utilization.

<p>(A) Distribution of the 67 E. coli strains across phylogroups used for validation. (B) Intra-phylogroup diversity of the validation set. Annotations indicate phylogroup, Mash cluster (distance threshold 0.02), genome count, and the fraction of genomes (%) assigned to each cluster. (C) Heat...

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Xehetasun bibliografikoak
Egile nagusia:	Omid Ardalani (22806506) (author)
Beste egile batzuk:	Patrick V. Phaneuf (6093296) (author), Jayanth Krishnan (22806509) (author), Siddharth M. Chauhan (11611162) (author), David Pride (3419807) (author), Daniel C. Zielinski (10048404) (author), Jonathan M. Monk (6732443) (author), Lars K. Nielsen (143479) (author), Bernhard O. Palsson (91399) (author)
Argitaratua:	2025
Gaiak:	Microbiology Genetics Molecular Biology Physiology Pharmacology Evolutionary Biology Ecology Infectious Diseases Virology Computational Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified stable drug targets minimal genetic diversity eschherichia coli </ escherichia coli </ div >< p depth analyses due maintaining metabolic functions core gene loss rare metabolic genes rare genes core genes metabolic robustness systematically investigate strains rely specific genome scale reconstruction scale models perceived redundancy open question microniche adaptation lost remains least one largely excluded high variability genome fluidity findings challenge evolutionary byproducts even costly considered non common view bacterial pangenomes >, revealing 15311 strain
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Experimental verification of panGEM predictions for carbon-source utilization.

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