Purification of peptide deletion mutants of PRV US1 proteins.

Purification of peptide deletion mutants of PRV US1 proteins.

<p>(A-F) The SUMO tag of recombinant SUMO-PRV US1 or its deletion mutant proteins was removed by SUMO protease treatment overnight at 4°C. The recombinant proteins PRV US1<sup>ΔA</sup> (A), PRV US1<sup>ΔB</sup> (C) and PRV US1<sup>ΔAB</sup> (E) were purified...

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書誌詳細
第一著者:	Weiyu Qu (16556638) (author)
その他の著者:	Ye Yuan (531126) (author), Dongdong Shen (11737395) (author), Jiwen Zhang (1501204) (author), Xiangyu Huang (8582868) (author), Lei Wu (202933) (author), Hongyan Yin (5066285) (author), Zhenchao Zhao (1417792) (author), Haiwei Wang (6864011) (author), Lvye Chai (16986157) (author), Jiayang Wu (5634650) (author), Xijun He (663738) (author), Cheng Zhu (138742) (author), Dongming Zhao (296447) (author), Xin Li (51274) (author)
出版事項:	2025
主題:	Biophysics Microbiology Molecular Biology Pharmacology Immunology Developmental Biology Infectious Diseases Virology Biological Sciences not elsewhere classified reduced viral loads including pseudorabies virus 1 -&# 916 spectrum antiviral vaccines herpesviruses remains elusive 1 us1 proteins xlink "> alpha prv -&# 916 herpesvirus us1 interacts herpesviruses antagonize cgas spectrum inhibitors directly interacts us1 protein wide range suppress type sting pathway promising target precise mechanisms peptides leads overlapping peptides mice infected increased cgas immune evasion ifn responses enzymatic activity enhanced signaling dsdna binding deficient viruses catalytic domain
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