Comparison of the predicted secondary structures for SELEX and Neomer libraries.

<p>A) Heatmap plot of the distribution of secondary structure motifs across 1000 randomly generated SELEX template sequences. Relative abundance is detailed in the legend on the right. B) FORNA RNAfold plotting of the secondary structure of the SELEX template sequence. Random nucleotides are s...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Cathal Meehan (14129680) (author)
مؤلفون آخرون:	Erika L. Hamilton (20715499) (author), Chloé G. Mansour (20715502) (author), Soizic Lecocq (4739196) (author), Cole J. Drake (20715505) (author), Yisi An (20715508) (author), Emily Rodrigues (8416182) (author), Gregory Penner (2408914) (author)
منشور في:	2025
الموضوعات:	Microbiology Molecular Biology Biotechnology Evolutionary Biology Immunology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified 29 × 10 selex method since neomers )</ p div >< p replicating immune tolerance driving aptamer specificity possible library sequences immune tolerance neomer library drive specificity new method method represents immune system aptamer selection aptamer identification vitro evolution structural diversity silico approach significant constraints significant constraint secondary structure remove antibodies random nucleotides powerful means novel platform high level fixed sequences counter selection commercial efficacy
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Comparison of the predicted secondary structures for SELEX and Neomer libraries.

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