Mitigation Strategies against Antibody Aggregation Induced by Oleic Acid in Liquid Formulations
Polysorbates 20 and 80 (PS20 and PS80) are commonly used in the formulations of biologics to protect against interfacial stresses. However, these surfactants can degrade over time, releasing free fatty acids, which assemble into solid particles or liquid droplets. Here, we apply a droplet microfluid...
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2024
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