Figure 4 from M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer

<p>Dose- and exposure-dependent inhibition of KIT autophosphorylation with M4205 in the GIST430/654 model. <b>A,</b> Tumor-bearing mice were treated daily with three different doses of M4205 for 5 days, and inhibition of KIT autophosphorylation compared with untreated controls was...

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第一著者:	Christina Esdar (16424072) (author)
その他の著者:	Nina Linde (16424066) (author), Andreas Blum (21644608) (author), Hanno Schieferstein (21644611) (author), Christine Drechsler (16424069) (author), Eva Sherbetjian (21644614) (author), Carl Petersson (21644617) (author), Edith Ross (21644620) (author), Birgitta Leuthner (17885856) (author), Ulrich Grädler (21644623) (author), Dieter Dorsch (21644626) (author), Andree Blaukat (15088980) (author)
出版事項:	2025
主題:	Cancer Cancer Biology Therapeutic Research and Development Oncogenes & Tumor Suppressors Oncogenes Sarcomas Small Molecule Agents Kinase inhibitors
タグ:	タグ追加タグなし, このレコードへの初めてのタグを付けませんか!

Figure 4 from M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer

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