Overcoming Fluorescence Interference: “Planar Hotspot” Substrates for Vitamin B Detection with SERS

Overcoming Fluorescence Interference: “Planar Hotspot” Substrates for Vitamin B Detection with SERS

Surface-enhanced Raman scattering (SERS) has demonstrated remarkable potential for molecular detection due to its specificity. However, detecting fluorescent vitamin B molecules remains challenging due to fluorescence interference and weak Raman cross-sections. To address this, we developed an innov...

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Bibliographic Details
Main Author: Liping Zhou (814435) (author)
Other Authors: Jin Sun (117866) (author), Rongheng Ma (20666846) (author), Xiaoming Lyu (417710) (author), Shimei Wang (2371510) (author), Jing Wu (54032) (author), Xuanyang Ding (21735050) (author), Zibo Gao (8315094) (author), Siqi Gong (436793) (author), Yingji Wang (16624716) (author), Yang Li (7082) (author)
Published: 2025
Subjects:
Biochemistry
Cell Biology
Molecular Biology
Pharmacology
Space Science
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Physical Sciences not elsewhere classified
Information Systems not elsewhere classified
weak raman cross
vitamin b detection
simulated biofluid environments
planar hotspot region
multifunctional detection platform
molecular detection due
integrating advanced machine
holds significant promise
enhanced raman scattering
demonstrated remarkable potential
amplifying raman signals
effectively quenching fluorescence
vitamin b molecules
overcoming fluorescence interference
fluorescence interference
target molecules
silver substrate
level analysis
learning algorithms
intelligent trace
innovative large
human samples
first time
direct interaction
detected high
design enables
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