The tetramer staining to detect the binding capacity of HLA-E/HTNV peptide complex to CD56<sup>dim</sup>CD16<sup>+</sup>NKG2A<sup>+</sup> NK cells in PBMCs from HFRS patients.

The tetramer staining to detect the binding capacity of HLA-E/HTNV peptide complex to CD56<sup>dim</sup>CD16<sup>+</sup>NKG2A<sup>+</sup> NK cells in PBMCs from HFRS patients.

<p>(A) Representative flow cytometric plots and (B) comparison of the frequencies of HLA-E/peptide (NP5 or GP8) tetramer<sup>+</sup> cells gated on CD56<sup>dim</sup>CD16<sup>+</sup>NKG2A<sup>+</sup>NKG2C<sup>-</sup>CD57<sup>-&l...

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Bibliographic Details
Main Author:	Manling Xue (14262008) (author)
Other Authors:	Kang Tang (722079) (author), Yusi Zhang (383393) (author), Xiaoyue Xu (712736) (author), Chunmei Zhang (67508) (author), Jiajia Zuo (10258540) (author), Fenglan Wang (11652412) (author), Xiyue Zhang (4288279) (author), Xuyang Zheng (3755152) (author), Ran Zhuang (383394) (author), Yun Zhang (131894) (author), Boquan Jin (383395) (author), Ying Ma (123771) (author)
Published:	2025
Subjects:	Biochemistry Medicine Molecular Biology Immunology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified infection remain unclear ex vivo </ div >< p detected using ligand cell rna sequencing antiviral immune response dim </ sup enhanced cytolytic capacity peptide affinity detection sup >-</ sup sup >+</ sup derived peptides presented α ), interferon virus infectious diseases receptor binding assay inhibitory receptor cd94 derived peptide complex nk cells showed derived peptides binding capacity nk cells cytotoxicity assay e cells tetramer staining taken together showing activation renal syndrome proliferation phenotypes pathogenesis process hemorrhagic fever hantaan virus functional evaluation flow cytometry findings demonstrate cytotoxic mediators
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