Porphyromonas gingivalis LPS pretreated by ozone ultrafine bubble water induces decreased TLR2 activation.

P. gingivalis LPS was added to distilled water (DW), air ultrafine bubble water (AUFBW), or 3.03 ppm ozone ultrafine bubble water (OUFBW). (A) HEK-Blue human Toll-like receptor 2 (hTLR2), (B) HEK-Blue hTLR4, and (C) HEK-Blue null2 cells were stimulated...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Mana Endo (22430706) (author)
مؤلفون آخرون:	Hisanori Domon (475574) (author), Satoru Hirayama (7106870) (author), Fumio Takizawa (397241) (author), Akiomi Ushida (15213552) (author), Koichi Tabeta (351272) (author), Yutaka Terao (343054) (author)
منشور في:	2025
الموضوعات:	Biochemistry Microbiology Molecular Biology Pharmacology Immunology Science Policy Hematology Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified toxin protein inactivation present study aimed like receptor 2 human gingival cells assess bactericidal activity porphyromonas gingivalis ,</ negative periodontal pathogen evaluated using hek porphyromonas gingivalis </ produces virulence factors oufbw suppressed lipoprotein mediated tlr4 signaling induced tlr2 activation div >< p gingivalis </ virulence factors negative bacteria western blotting various bacteria tissue destruction silver staining results suggest oufbw would oufbw disrupted mtt assay morphological changes membrane vesicles inner membrane inhibited gingipain induced degradation gingipain breakdown gingipain activities findings indicate endogenous substrates culture supernatant analyzed using >, leading
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<i>Porphyromonas gingivalis</i> LPS pretreated by ozone ultrafine bubble water induces decreased TLR2 activation.

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