A small outbreak in which individual i infects individual k, who then infects individual j, along with sampled genetic sequences from each individual.

Grey circles and lines represent unobserved timepoints and events, such as the exact transmission time from individual i j, and the number of mutations that occur between events, denoted by . Genetic sequences for the individuals are sampled at timepoin...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Hannah Waddel (21520023) (author)
مؤلفون آخرون:	Katia Koelle (82611) (author), Max S. Y. Lau (9128033) (author)
منشور في:	2025
الموضوعات:	Biophysics Medicine Genetics Biotechnology Evolutionary Biology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified major scalability issue infinite sites assumption existing phylodynamic approaches validated modeling framework phylodynamic modeling framework unobserved dynamics including temporal phylodynamic framework scalable bayesian inference genomic data collected effective outbreak responses accurate modeling framework method scales significantly mechanistically integrate epidemiological div >< p evolutionary dynamics including transmission dynamics consistent mouth disease outbreak unobserved transmission tree temporal dynamics evolutionary dynamics disease transmission transmission tree yet accurate highly scalable outbreak size modeling mutation evolutionary processes evolutionary process tree </ without relying various non underlying epidemiological sequence level results show results indicate readily deployable r package prior method previous work previous method powerful tool outbreaks continues nucleotide level new approach mostly rely modeled explicitly method ’ method provides large outbreaks joint spatio
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الوصف
الملخص:	<p>Grey circles and lines represent unobserved timepoints and events, such as the exact transmission time from individual <i>i</i> <i>j</i>, and the number of mutations that occur between events, denoted by . Genetic sequences for the individuals are sampled at timepoints .</p>

A small outbreak in which individual i infects individual k, who then infects individual j, along with sampled genetic sequences from each individual.

مواد مشابهة