Protocol of a target trial to estimate the effect of paxlovid on the rate of hospitalization in the 28 days following a positive SARS-CoV-2 test.

Protocol of a target trial to estimate the effect of paxlovid on the rate of hospitalization in the 28 days following a positive SARS-CoV-2 test.

<p>Protocol of a target trial to estimate the effect of paxlovid on the rate of hospitalization in the 28 days following a positive SARS-CoV-2 test.</p>

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Bibliographic Details
Main Author:	Abhishek Bhatia (15224489) (author)
Other Authors:	Alexander J. Preiss (20577505) (author), Xuya Xiao (20577508) (author), M. Daniel Brannock (18766501) (author), G. Caleb Alexander (7854044) (author), Robert F. Chew (4397755) (author), Hannah Davis (9570767) (author), Megan Fitzgerald (14875194) (author), Elaine Hill (1506340) (author), Elizabeth P. Kelly (20577511) (author), Hemalkumar B. Mehta (8811044) (author), Charisse Madlock-Brown (12421168) (author), Kenneth J. Wilkins (13205077) (author), Christopher G. Chute (8754639) (author), Melissa Haendel (14045) (author), Richard Moffitt (12043127) (author), Emily R. Pfaff (17285101) (author)
Published:	2025
Subjects:	Medicine Neuroscience Biotechnology Cancer Mental Health Infectious Diseases Virology target trial assessing severe disease due electronic health record covariates including sex coronavirus disease 2019 similar among patients paxlovid &# 8217 among younger patients united states alone reducing severe covid hospitalization among adults absolute risk reduction 9 percentage points 2 percentage points paxlovid remains uncertain xlink "> nirmatrelvir 19 index date n3c </ p xlink "> united states remains true p </ latino patients 647 patients world data weight technique vaccination status unknown whether several studies secondary outcome risk factors protective association primary outcome preventing hospitalization positive test patient ’ omicron subvariants main limitation local cohorts inverse probability diagnosis ). confidence interval community well clinical trials censoring weights care provision august 28 2 ]; 19 seen 19 index 001 ). 001 ),
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