Fig 1 -

Fig 1 -

<p>(A) Starting from single-cell data (I), we obtain the distance matrix of cells in PCA space (III) and the GRN of individual cells (II). By solving the Euclidean distance of cells in the space characterized by the out-degree and in-degree of all genes, we obtain the cell distance matrix (IV)...

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Bibliographic Details
Main Author: Rui Sun (177521) (author)
Other Authors: Wenjie Cao (780652) (author), ShengXuan Li (20324240) (author), Jian Jiang (566504) (author), Yazhou Shi (20324243) (author), Bengong Zhang (11556727) (author)
Published: 2024
Subjects:
Cell Biology
Genetics
Biotechnology
Immunology
Developmental Biology
Cancer
Hematology
Plant Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
xlink "> research
minimum spanning tree
gene regulatory networks
gene regulation network
cell rna sequencing
cell differentiation trajectory
cell differentiation facilitates
incorporating dynamic changes
gene expression space
unlike existing approaches
data primarily rely
cell data
grn space
dynamic relationships
existing state
existing methods
cell entropy
undirected graph
superior performance
static relationships
seq data
precision medicine
novel method
measure distances
grn ).
fundamental processes
deeper understanding
comparative analysis
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