Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif

Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif

Introduction<p>Small extracellular vesicle (sEV)-based therapies have gained widespread interest, but challenges persist to ensure standardization and high-scale production. Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely...

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Bibliographic Details
Main Author: Thibaud Dauphin (21196820) (author)
Other Authors: Laurence de Beaurepaire (9442964) (author), Apolline Salama (627431) (author), Quentin Pruvost (21196823) (author), Clémentine Claire (21196826) (author), Karine Haurogné (778191) (author), Sophie Sourice (292787) (author), Aurélien Dupont (5673128) (author), Jean-Marie Bach (627439) (author), Julie Hervé (6423839) (author), Eric Olmos (21196829) (author), Steffi Bosch (9442988) (author), Blandine Lieubeau (778193) (author), Mathilde Mosser (9442973) (author)
Published: 2025
Subjects:
Biotechnology
spheroid
extracellular vesicles
bioreactor
bioproduction
bioprocess
scale-up
shear stress
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