False-negative cases of NIPT.

<div><p>Objective</p><p>Genome-wide non-invasive prenatal testing (GW-NIPT) for prenatal screening has been widely implemented. However, the related clinical data is still insufficient. Here, we evaluated the clinical performance of GW-NIPT as a first-tier screening test for...

Full description

Saved in:

Bibliographic Details
Main Author:	Jianxin Zhen (6956498) (author)
Other Authors:	Liting Zhang (2883890) (author), Huilin Wang (620172) (author), Xi Chen (35903) (author), Weihong Wang (115331) (author), Lili Li (42450) (author), Quanfu Zhang (158693) (author)
Published:	2025
Subjects:	Medicine Cell Biology Genetics Molecular Biology Biotechnology Developmental Biology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified sex chromosome aneuploidy rare autosomal aneuploidy positive predictive values invasive diagnostic procedures including 5 cases copy number variation children &# 8217 877 pregnant women 5 &# 8201 9 %, respectively 9 %, 2 8 %, 10 3 %, 51 1 %, 25 tier screening test chromosomal microarray analysis related clinical data moderate clinical utility invasive prenatal testing cnv (&# 8805 screening fetal aneuploidy fetal karyotype analysis detecting fetal aneuploidy confirmed fetal mosaicism study included 59 xlink "> gw xlink "> genome xlink "> prenatal screening fetal mosaicism detecting cnv fetal aneuploidies analysis demonstrated clinical performance clinical experience 6 %, 0 %, widely implemented wide non underwent gw successfully tested still insufficient situ hybridization postnatal outcomes november 2017 may 2021 high sensitivity detection rate 504 high 500 platform
Tags:	Add Tag No Tags, Be the first to tag this record!

False-negative cases of NIPT.

Similar Items