MitoTracer identified essential primary BRAF inhibitor-resistant genes.

<p>(A)The reconstructed lineage was visualized by heatmap from MitoTracer. All these cells were clustered into two major clusters labeled “Cluster_1” and “Cluster_2”. Cells were labeled according to their original BRAF inhibitor resistance status, “Resistant” and “Parental”. We also labeled th...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Xuexin Yu (733842) (author)
مؤلفون آخرون:	Jing Hu (41899) (author), Yuhao Tan (15227659) (author), Mingyao Pan (21587178) (author), Hongyi Zhang (431841) (author), Bo Li (112195) (author)
منشور في:	2025
الموضوعات:	Genetics Molecular Biology Evolutionary Biology Cancer Infectious Diseases Plant Biology Biological Sciences not elsewhere classified Information Systems not elsewhere classified xlink "> mitochondrial natural genetic markers mutated cancer cells inferred evolutionary lineage existing methods measured informative mitochondrial mutations benchmarked mitotracer using based lineage tracing informative mt mutations mutations serve work provided valuable tool superior performance mt mutation mitotracer facilitates inhibitor resistance high sensitivity genes related fundamental challenge
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MitoTracer identified essential primary BRAF inhibitor-resistant genes.

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