SAS-1 is dispensable for centriole assembly but essential for organelle integrity.

SAS-1 is dispensable for centriole assembly but essential for organelle integrity.

<p><b>A.</b> Snapshots from live imaging of early embryo stemming from mating males expressing TagRFP-T::SAS-7 with <i><i>sas-1(is13)</i></i> mutant hermaphrodite expressing SAS-4::GFP (see S3C–S3E Fig). TagRFP-T::SAS-7 marks sperm-contributed centrioles (in...

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Bibliographic Details
Main Author: Keshav Jha (13805097) (author)
Other Authors: Alexander Woglar (204503) (author), Coralie Busso (3610127) (author), Georgios N. Hatzopoulos (16763834) (author), Tatiana Favez (22478147) (author), Pierre Gönczy (434319) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Cell Biology
Genetics
Neuroscience
Physiology
Immunology
Developmental Biology
Cancer
Mental Health
Computational Biology
Physical Sciences not elsewhere classified
partially redundant manner
molecular epistasis experiments
findings help clarify
based organelles critical
1 localizes next
div >< p
binding protein sas
ensures centriole integrity
1 recruits ssna
centriole integrity
organelle integrity
centriole assembly
centriole architecture
1 localization
transition zone
sjögren ’
sensory neurons
null alleles
null allele
incompletely understood
elegans </
early embryo
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