Methods for specifying variant-specific prior probabilities.

<p>Methods for specifying variant-specific prior probabilities.</p>

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Jeffrey M. Pullin (18059944) (author)
مؤلفون آخرون:	Chris Wallace (210182) (author)
منشور في:	2025
الموضوعات:	Cell Biology Genetics Molecular Biology Infectious Diseases Virology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified tss distance densities improve colocalisation performance compare six source eqtl &# 8211 use additional information statistical colocalisation analysis gene link scores specifying prior probabilities specific prior probabilities widely used method eqtl colocalisations variant prior probabilities specifying variant specific priors link gwas eqtl colocalisations eqtl associations polyfun method coloc method using simulations three estimates ongoing challenge mapping methods loci revealing equally likely context remains coloc package coloc assumes coding constraint causal gene
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