Genetic modification of <i>ciaRH</i> thermosensing element disrupts PCho levels and pneumococcal invasion efficiency.

Genetic modification of <i>ciaRH</i> thermosensing element disrupts PCho levels and pneumococcal invasion efficiency.

<p><b>A-B.</b> Cartoon representation of predicted secondary structures of 5′-UTR<sub>Closed</sub><i>ciaRH</i> (<b>A</b>) and 5′-UTR<sub>Open</sub><i>ciaRH</i> (<b>B</b>) by mFold. List of mutations introduced...

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Bibliografische gegevens
Hoofdauteur:	Shruti Apte (8658996) (author)
Andere auteurs:	Greicy K. Bonifacio-Pereira (22339795) (author), Sourav Ghosh (184217) (author), Srijit Kumar Mandal (22339798) (author), Leena Badgujar (22339801) (author), Krithika Gosavi (22339804) (author), Elizabeth Pohler (22339807) (author), Thomas E. Barton (16940866) (author), Sian Pottenger (15258044) (author), Alice Blake (22339810) (author), Pradeepkumar PI (22339813) (author), Daniel R. Neill (7633586) (author), Anirban Banerjee (275341) (author)
Gepubliceerd in:	2025
Onderwerpen:	Medicine Microbiology Cell Biology Immunology Infectious Diseases Virology Space Science Environmental Sciences not elsewhere classified trigger behavioral change streptococcus pneumoniae </ signaling arm could influencing infection outcomes induced bacteraemic pneumonia global regulator ciar div >< p dictating pleiotropic phenotypes create translation restrictive changing niche ecosystem minor temperature shifts minor temperature oscillations including temperature fluctuations opportunistic pathogens switch thermosensing master regulator necessitating efficient sensing pcho mitigated spn elevated temperature rna thermosensing master regulators virulent lifestyles untranslated region typically achieved rapid integration positively regulating pivotal role pcho ), pathogenic state pathogen switch mediated via intranasal administration environmental cues element within
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