Bacterial growth load (CFUs) and average of NH<sub>3</sub> ppm across the cage-change cycle in cages changed bi-weekly (filled circles) vs. weekly (open circles).

Bacterial growth load (CFUs) and average of NH<sub>3</sub> ppm across the cage-change cycle in cages changed bi-weekly (filled circles) vs. weekly (open circles).

<p>Data from male and female cages are colour coded, see key in diagram. Inserted in the diagram is a box plot of bacterial load for both samples and the obtained p-value for the statistical pair-test (Wilcoxon matched pair).</p>

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	B. Ulfhake (6293984) (author)
مؤلفون آخرون:	H. Lerat (12635796) (author), J. Honetschlager (12635799) (author), K. Pernold (12635802) (author), M. Rynekrová (12635805) (author), K. Escot (12635808) (author), C. Recordati (2608873) (author), R. V. Kuiper (12635811) (author), G. Rosati (6293972) (author), M. Rigamonti (6293969) (author), S. Zordan (12635814) (author), J.-B. Prins (12635817) (author)
منشور في:	2022
الموضوعات:	Cell Biology Genetics Molecular Biology Neuroscience Evolutionary Biology Developmental Biology Cancer Science Policy Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified upper airways covarying therefor examined longitudinally reach &# 8804 individually ventilated cages histopathological analysis revealed gradual decrease till 50 &# 8211 0 &# 8211 latrine free part replicated across sites div >< p male mice allocate latrine free area latrine area decreased latrine area compared change </ p two mice abolished next cage change shorter cc interval ivc housed c57bl entire cage floor cage floor already weekly cage change male mice preferred second week activity reducing housing density female mice used latrine area two mice cage change cage floor weekly cage male c57bl opposite area mice respond 6j mice cage activity ppm across prevailing routine potential threat overt discomfort multicentre study multicentre design marked increase ivcs ). issue unresolved increased anxiety first week equivalent biomass environmental conditions disrupted sleep described conditions consecutive cycles cc induce bedding used bacterial load animals rest animal health altered activity 10 weeks
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