Assessment of TCR contacts with the pMHC in the MHC-I and MHC-II test sets.

<p><b>(A)</b> The upper panels show contacts between the TCRα variable domain and the peptide or MHC-I, while the lower panels display contacts between the TCRβ variable domain and the peptide or MHC. The left panels detail TCRα and TCRβ contacts with the MHC-I, and the right panel...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Helder V. Ribeiro-Filho (15188347) (author)
مؤلفون آخرون:	Gabriel E. Jara (19762506) (author), João V. S. Guerra (19762509) (author), Melyssa Cheung (17440005) (author), Nathaniel R. Felbinger (19762512) (author), José G. C. Pereira (19762515) (author), Brian G. Pierce (204648) (author), Paulo S. Lopes-de-Oliveira (15388693) (author)
منشور في:	2024
الموضوعات:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Biotechnology Immunology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified unique natural characteristics shown promising results mediating immune responses existing ones designed evaluate tcr designs different design scenarios infected target cells based design methods target protein based metrics based methods design field computational design treating diseases substantially impacted specific functions protein modeling particularly due novel proteins low affinity increasing set identifying deficiencies especially cancer designing fixed current physics crucial role comprehensive set classical physics cell receptors
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Assessment of TCR contacts with the pMHC in the MHC-I and MHC-II test sets.

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