Assessment of TCR contacts with the pMHC in the MHC-I and MHC-II test sets.
<p><b>(A)</b> The upper panels show contacts between the TCRα variable domain and the peptide or MHC-I, while the lower panels display contacts between the TCRβ variable domain and the peptide or MHC. The left panels detail TCRα and TCRβ contacts with the MHC-I, and the right panel...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2024
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
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| الملخص: | <p><b>(A)</b> The upper panels show contacts between the TCRα variable domain and the peptide or MHC-I, while the lower panels display contacts between the TCRβ variable domain and the peptide or MHC. The left panels detail TCRα and TCRβ contacts with the MHC-I, and the right panels show TCRα and TCRβ contacts with the peptide. Contacts are identified by TCR position, using the Aho numbering scheme, with CDR positions indicated. The y-axis represents the number of structures (total of 32 in the MHC-I test set) where each contact is observed. <b>(B)</b> same as (A) but considering contacts with the peptide and MHC in the MHC-II test set (total of 6 structures).</p> <p>(TIF)</p> |
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