Cnot4 Het does not affect mRNA expression of metabolic genes as well as serum lipid levels or glucose tolerance.

<p>(A, B) mRNA levels of lipid metabolic genes in mouse livers (A) and WATs (B). (n = 3). (C) Blood triglyceride and cholesterol level in mice. (D) Glucose tolerance test. Mice were fasted for 16 hours prior to the experiment. Blood glucose levels in mice were measured at the indicated times f...

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Main Author:	Tomokazu Yamaguchi (8284989) (author)
Other Authors:	Midori Hoshizaki (13141011) (author), Yumiko Imai (128156) (author), Tadashi Yamamoto (162395) (author), Keiji Kuba (366932) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Physiology Developmental Biology Computational Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified wild type fibroblasts white adipose tissue several subunits within serum lipid levels ppar &# 947 including significant reduction high fat diet hepatic lipid depots e3 ubiquitin ligase adipose tissue partly adipose tissue mass affect mrna expression obesity remain unexplored mice exhibit resistance mrna poly transcriptional activity thereby suppressing target gene results suggest promoter region metabolic genes major executor induced obesity heterozygous deletion glucose tolerance energy metabolism decreased binding also associated
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Cnot4 Het does not affect mRNA expression of metabolic genes as well as serum lipid levels or glucose tolerance.

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