Pathophysiology of the localized radiation injury at early timepoints.

<p>(A) Experimental design. Two independent mice cohorts were used to perform a broad-spectrum profiling of miRNAs (cohort 1) and then a targeted study (cohort 2) for each time points (D1 and D7, end of experiment). For each cohort, mice were irradiated on their left hindlimb according to 4 ir...

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Bibliographic Details
Main Author:	Lucie Ancel (22022065) (author)
Other Authors:	Jules Gueguen (22022068) (author), Guillaume Thoër (22022071) (author), Jules Marçais (22022074) (author), Aïda Chemloul (22022077) (author), Bernard Le Guen (10896352) (author), Marc Benderitter (168382) (author), Radia Tamarat (5965670) (author), Maâmar Souidi (6815306) (author), Mohamed Amine Benadjaoud (4172245) (author), Stéphane Flamant (14912708) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Neuroscience Biotechnology Immunology Developmental Biology Cancer Biological Sciences not elsewhere classified Physical Sciences not elsewhere classified symptom onset ranging refine mirna signatures prognostic mirna signatures clinical symptoms appear based biomarker signatures two latency stages identified candidate mirnas da ), signatures localized radiation injury mice </ p localized radiation injuries day 14 clinical early lri diagnosis lri severity prognosis mirnas ), localized injuries early diagnosis lri severity unrelated mice radiation response radiation exposure latency phase tissue injuries day 7 day 1 diagnosing lri xlink "> used throughout treatment outcomes tissue necrosis tissue damage severe outcomes previously associated presymptomatic microrna powerful tool performed broad mouse model irradiation ). hindlimb irradiation functional outcomes effective triage dose groups different severities adapted treatment 7 post
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Pathophysiology of the localized radiation injury at early timepoints.

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