Univariate and multivariate Cox analysis.

Univariate and multivariate Cox analysis.

<div><p>Background</p><p>The current study aims to elucidate the key molecular mechanisms linked to endoplasmic reticulum stress (ERS) in the pathogenesis of sepsis-induced cardiomyopathy (SIC) and offer innovative therapeutic targets for SIC.</p><p>Methods</p&...

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Bibliographic Details
Main Author: Wan-Jing Zhen (20427813) (author)
Other Authors: Yan Zhang (8098) (author), Wei-Dong Fu (20427816) (author), Xiao-Lei Fu (20427819) (author), Xin Yan (17064) (author)
Published: 2024
Subjects:
Biochemistry
Cell Biology
Genetics
Molecular Biology
Immunology
Marine Biology
Infectious Diseases
Biological Sciences not elsewhere classified
providing fresh perspectives
identify key modules
endoplasmic reticulum stress
septic mice compared
related gene set
current study aims
1327 key genes
serum pdhb levels
decreased pdhb mrna
expression network analysis
13 hub genes
protein expression levels
protein interaction network
potential sic pathogenesis
sic hub genes
related genes
hub genes
protein interaction
network construction
study elucidated
septic patients
genes associated
hub module
pdhb emerged
xlink ">
vivo experiments
validated using
significant biomarker
prognostic significance
prognostic models
novel insights
lasso algorithm
induced cardiomyopathy
enrichment analyses
encompassing go
clinical significance
cibersort algorithm
cardiac tissue
based hubs
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