Image 1_Direct and indirect RANK and CD40 signaling regulate the maintenance of thymic epithelial cell frequency and properties in the adult thymus.tif

Image 1_Direct and indirect RANK and CD40 signaling regulate the maintenance of thymic epithelial cell frequency and properties in the adult thymus.tif

<p>Medullary thymic epithelial cells (mTECs) play a crucial role in suppressing the onset of autoimmunity by eliminating autoreactive T cells and promoting the development of regulatory T cells in the thymus. Although mTECs undergo turnover in adults, the molecular mechanisms behind this proce...

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Bibliographic Details
Main Author: Mio Hayama (17322436) (author)
Other Authors: Hiroto Ishii (20357043) (author), Maki Miyauchi (558093) (author), Masaki Yoshida (5437) (author), Naho Hagiwara (17322439) (author), Wataru Muramtatu (20357046) (author), Kano Namiki (17322430) (author), Rin Endo (20357049) (author), Takahisa Miyao (7486901) (author), Nobuko Akiyama (558091) (author), Taishin Akiyama (264066) (author)
Published: 2024
Subjects:
Genetic Immunology
thymic epithelial cell (TEC)
self-tolerance
TNF receptor (TNFR) family
progenitor
AIRE
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