Samples & cell type composition in sc/snRNA-seq.

Samples & cell type composition in sc/snRNA-seq.

<div><p>Melanoma brain metastasis (MBM) remains lethal with limited treatment efficacy. Meanwhile, the cellular origins and drivers of brain metastasis from melanoma have yet to be defined. Through integrated single-cell/single-nucleus RNA sequencing of 26 melanoma samples, we identified...

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Xehetasun bibliografikoak
Egile nagusia:	Jingxin Zeng (18773484) (author)
Beste egile batzuk:	Ling Lin (57361) (author), Yangyang Ma (6329852) (author), Wenzhe Huang (446343) (author), Quan Luo (1423180) (author), Ju Wen (14784239) (author)
Argitaratua:	2025
Gaiak:	Cell Biology Genetics Neuroscience Biotechnology Immunology Developmental Biology Cancer Hematology Virology Biological Sciences not elsewhere classified Information Systems not elsewhere classified limited treatment efficacy associated tumor cells adhesion genes (< nucleus rna sequencing metastatic tumor subpopulation 26 melanoma samples study identifies mbmatcs mbm ecosystems showed div >< p melanoma brain metastasis metastatic pathways bulk rna brain metastasis melanoma patients validation cohorts upregulated neural treg enrichment remains lethal potential activity nrg3 </ ncam1 </ mela3 ). lag3 </ high risk havcr2 </ early stratification clinical relevance cellular origins cellular origin brain tropism >), suggesting 1 </
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Antzeko izenburuak

scRNA-seq and snRNA-seq profiling of 26 melanoma samples.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Marker genes in melanoma tumor cells across PT, ECM and MBM by sc/snRNA-seq.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Single cell RNA-seq and snRNA-seq profiling of the PTs (primary melanoma), ECMs (extracranial melanoma metastases) and MBMs (melanoma brain metastases) environments.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Fluvastatin inhibits the migration of melanoma A375 cells in a wound healing assay.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Discovery of therapeutic compounds targeting brain metastasis-associated tumor cells (MBMATCs) in high MBM-Index melanoma.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

The MBM-Index as an independent predictor of overall survival (OS) in melanoma.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Identification of melanoma brain metastasis-associated tumor cell subpopulations (MBMATCs).
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Tumor cell-specific transcriptomic features across PTs, ECMs and MBMs.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Immune landscape and CD8<sup>+</sup> T cell transition states in PTs, ECMs and MBMs.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Samples & cell type composition in melanoma tumor cells.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

AXL and MITF signature genes.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Identification of therapeutic drugs with high drug sensitivity for brain metastasis-associated tumor cells (MBMATCs) and high-brain metastasis (MBM) index patients.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

The enriched pathway by all transcripts differentially expressed between MBMATCs and other tumor cells, and between MBM-High and MBM-Low groups.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

The MBM-Index showed no significant correlation with clinicopathological features.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Interaction between MBMATCs and the immune microenvironment.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Pseudotime trajectory analysis of melanoma clusters Mela4 and Mela5.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Immune cells profiling in PTs, ECMs and MBMs.
nork: Jingxin Zeng (18773484)
Argitaratua: (2025)

Processed snRNA-seq data from wild-type and <i>Pink1</i>-deficient mouse gut
nork: Muhammad Junaid (14524523)
Argitaratua: (2025)

scRNA-seq, Oligodendrocyte-Lineage Meta-Atlas
nork: Nicholas Mikolajewicz (11242755)
Argitaratua: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
nork: Matthia A. Karreman (15097355)
Argitaratua: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
nork: Matthia A. Karreman (15097355)
Argitaratua: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
nork: Matthia A. Karreman (15097355)
Argitaratua: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
nork: Matthia A. Karreman (15097355)
Argitaratua: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
nork: Matthia A. Karreman (15097355)
Argitaratua: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
nork: Matthia A. Karreman (15097355)
Argitaratua: (2025)

Supplementary Table 1 from Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
nork: Nneoma Adaku (16991063)
Argitaratua: (2025)

Supplementary Table 2 from Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
nork: Nneoma Adaku (16991063)
Argitaratua: (2025)

Supplementary Table 3 from Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
nork: Nneoma Adaku (16991063)
Argitaratua: (2025)

Classification of Udai21 and the World Rice Core Collection based on ddRAD-Seq data.
nork: Hiroki Ikeda (510280)
Argitaratua: (2025)

Processed single-cell RNA-seq dataset of cancer-associated fibroblasts in breast cancer patients receiving anti–PD-1 therapy
nork: Thang Pham (19938126)
Argitaratua: (2025)

Data Sheet 1_The role of microRNAs and long non-coding RNAs in epigenetic regulation of T cells: implications for autoimmunity.pdf
nork: Soumil Prasad (22679354)
Argitaratua: (2025)

<b>Engineered </b><b>VPg</b><b> </b><b>saRNA achieves cap-independent,</b><b> </b><b>low-immunogenic and precise</b><b> </b><b>encoding of therapeutic proteins </b><b>in vivo</b><b>.</b>
nork: Zunyong feng (22673801)
Argitaratua: (2025)

Extended Data Figure 7 – Source Data (corticocortical L2/3 synaptic transmission in Wfs1-CreERT2 mice)
nork: Jinseon Yu (22598699)
Argitaratua: (2025)

Synthetic Aperture Radar as a Tool for Tornado Classification in Forested Areas
nork: Sophia G. Slabon (22677053)
Argitaratua: (2025)

Original data for figure in the article<b> “</b><b>Genome-wide characterization of Toll-like receptor genes in </b><b><i>Oreochromis niloticus</i></b><b> and their involvement in brain immune response against </b><b><i>Streptococcus agalactiae</i></b><b> infection”</b>
nork: Xitan Hou (22677809)
Argitaratua: (2025)

Category-level summary of genes with potentially distinct functions between Udai21 and Koshihikari.
nork: Hiroki Ikeda (510280)
Argitaratua: (2025)

Statistics for Udai21 pseudomolecule sequences.
nork: Hiroki Ikeda (510280)
Argitaratua: (2025)

Genome assembly and predicted gene BUSCO scores.
nork: Hiroki Ikeda (510280)
Argitaratua: (2025)

Genome assembly statistics for Udai21.
nork: Hiroki Ikeda (510280)
Argitaratua: (2025)

Classification of Udai21 and the World Rice Core Collection based on organelle genome data.
nork: Hiroki Ikeda (510280)
Argitaratua: (2025)

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