ITC Binding Isotherms of Tafamidis, SFL001535, 94320297 and SEL101928.

ITC Binding Isotherms of Tafamidis, SFL001535, 94320297 and SEL101928.

<p>Isotherms of tested compounds along with calculated K<sub>d</sub> values and standard error of curve fitting are shown. Isotherm of Tafamidis appeared to be sigmoidal (<b>A.</b>) whilst binding cooperativity was evident for Compound 94320297 (<b>B.</b>),...

Full description

Saved in:

Bibliographic Details
Main Author:	Wenjie Chen (130753) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Molecular Biology Neuroscience Pharmacology Biotechnology Cancer Infectious Diseases Chemical Sciences not elsewhere classified two lead molecules thyroxine displacement ic thyroxine displacement assay subsequent analogue screens capillary zone electrophoresis 16 initial hits free ligand known confirmation rate ). based drug discovery similar itc k div >< p 125 </ sup fragment screening methodology probe ligand hit rate fragment screening fluorescence based </ sub xlink "> transthyretin amyloidosis procedurally simple neat plasma monitors changes fpphr ), derived compounds competing fragments circular dichroism causing amyloidosis 129 fragments
Tags:	Add Tag No Tags, Be the first to tag this record!

Cannot write session to /tmp/vufind_sessions/sess_e4790l144c6f4no70hrkv833gs