PPI Network and Module Identification of Sepsis-Related Genes.

<p>(A) PPI network of up-regulated sepsis-related genes, constructed using the STRING database, illustrating key molecular interactions and their potential roles in sepsis pathogenesis. (B) PPI network of down-regulated sepsis-related genes, visualizing distinct functional interactions among t...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Yiping Lang (21560364) (author)
مؤلفون آخرون:	Tianyu Liang (8493861) (author), Fei Li (143236) (author)
منشور في:	2025
الموضوعات:	Medicine Cell Biology Genetics Molecular Biology Immunology Cancer Infectious Diseases Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified recent studies suggest provide new ideas pronounced alterations observed lasso cox regression highly advantageous method evaluated using cibersort elastic net regularization complex molecular alterations six key genes receiver operating characteristic individual genes across potential application value independent hf datasets characteristic genes related genes auc value validation datasets related datasets potential role potential biomarkers xlink "> study aimed single gene significantly higher screened may risk stratification risk score predictive modeling predicting hf integrated multi immune infiltration identified 340 hf patients hf based help improve heart failure gse5406 ). glmnet package gene signatures gene signature efficient values early diagnosis developed based combat algorithm clinical management cecal ligation cardiovascular dysfunction auc values 6 mice
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PPI Network and Module Identification of Sepsis-Related Genes.

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