pone.0337200.t001 -

pone.0337200.t001 -

<div><p>Evogliptin, an anti-diabetic drug had positive impact on various cardiovascular events including inflammation and vascular calcification (VC), an active process driven by vascular smooth muscle cell (VSMC) phenotypic transition. Sphingolipids such as ceramide (CER) mediates infla...

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Bibliographic Details
Main Author: Razia Rashid Rahil (22772495) (author)
Other Authors: Salman Shamas (22772498) (author), Nissar Ahmad Wani (13005843) (author), Neha Nanda (2575573) (author), Sheikh Fayaz Ahmad (22772501) (author), Sabry Mohamed Attia (22772504) (author), Abid Hamid (545012) (author), Mohammad Afzal Zargar (18783230) (author), Owais Mohmad Bhat (18783227) (author)
Published: 2025
Subjects:
Microbiology
Cell Biology
Genetics
Molecular Biology
Neuroscience
Physiology
Pharmacology
Biotechnology
Evolutionary Biology
Immunology
Developmental Biology
Cancer
Infectious Diseases
Virology
alizarin red staining
active process driven
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calcification via modulation
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blocking phenotypic transition
evogliptin prevents ceramide
evogliptin alleviates vc
phenotypic transition
vascular calcification
severe calcification
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vc ),
vascular tissue
underlying cause
stimulation led
pyroptotic markers
prior treatment
positive impact
osteogenic markers
mediates inflammation
mediated pathway
marked upregulation
ldh release
increased expression
diabetic drug
data demonstrate
control cells
cleavage efficiency
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