Integrated genomic analysis of the association at 7q33 with cleft lip and palate (CLP).

مواد مشابهة

• Integrated genomic analysis of the association at 8q22.1 with cleft lip and palate (CLP).
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Integrated genomic analysis of the association at 16p13.3 with cleft lip with or without cleft palate (CL/P).
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Sample size by phenotype and ancestry group.
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Significantly enriched Gene Ontology (GO) terms among the 512 genes showing significant results in the all ancestry TWAS. Enrichment analyses were conducted using the multi-query in g:Profiler [16]. Columns include source, term name, GO id, and adjusted p-values across each phenotype definition. P-values were adjusted to maintain an experiment-wide type 1 error rate of 0.05 using the g:SCS algorithm which accounts for the dependent structure of functionally annotated gene sets.
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Results from genome-wide all ancestry meta-analysis for each independent lead variant demonstrating genome-wide significance (p < 5e-8) in at least one phenotype. Columns include Chromosome (Chr), position (hg38), reference and alternate (effect) alleles (Ref/Alt), rsID, candidate gene (either the gene nearest the variant or a previously implicated risk gene), direction of effect (Dir) on any cleft for POFC1, POFC2, and GENEVA OFC, respectively (? indicates variant was not present in that study), and p-values and from meta-analysis across each phenotype definition.
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)