Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging

Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging

<p>Glaucoma is a major cause of blindness globally and its prevalence rises with age. This study explored systemic blood-derived DNA methylation epigenetic biomarkers for association with glaucoma and intraocular pressure (IOP). Blood-derived DNA methylation (DNAm) was analyzed in 1,201 Europe...

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Bibliographic Details
Main Author: Xiaofan Jiang (8962256) (author)
Other Authors: Omar A. Mahroo (13844402) (author), Anthony P Khawaja (22453908) (author), Dorota Skowronska-Krawczyk (79619) (author), David A. Mackey (9425653) (author), Janey L. Wiggs (10789680) (author), The International Glaucoma Genetics Consortium, Christopher J. Hammond (22453911) (author), Pirro G. Hysi (7634090) (author), Christopher G. Bell (7308839) (author)
Published: 2025
Subjects:
Biochemistry
Medicine
Cell Biology
Genetics
Molecular Biology
Physiology
Pharmacology
Biotechnology
Cancer
Mental Health
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Glaucoma
intraocular pressure
Epigenetics
DNA methylation
biomarkers
CLSA
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