Polo-like kinase 1 (PLK1) induces Vemurafenib resistance in melanoma.

Polo-like kinase 1 (PLK1) induces Vemurafenib resistance in melanoma.

<p><b>(A)</b> Relative cell viability under the treatment of Vemurafenib in mouse melanoma cells (mMC) and mouse melanoma with Plk1 knock-in (mMPI) cells. <i>n</i> = 3 biological replicates. Mean ± SD. n.s., <i>P</i> > 0.05; * <i>P</i> < 0....

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Príomhchruthaitheoir: Fengyi Mao (15073242) (author)
Rannpháirtithe: Sai Wu (6096290) (author), Derek B. Allison (15141675) (author), Daheng He (9189701) (author), Yifan Kong (4458616) (author), Chaohao Li (15141681) (author), Zhiguo Li (431917) (author), Yanquan Zhang (14930570) (author), Xinyi Wang (559030) (author), Qiongsi Zhang (2818111) (author), Chi Wang (131921) (author), Xiaoqi Liu (45630) (author)
Foilsithe / Cruthaithe: 2025
Ábhair:
Cell Biology
Genetics
Molecular Biology
Developmental Biology
Cancer
Hematology
Biological Sciences not elsewhere classified
suppress tumor growth
like kinase 1
crucial transcription factor
cnc homolog 1
clinical database analysis
shortened mice survival
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synergistic efficiency
novel function
negatively correlates
genes involved
cell cycle
cancer progression
cancer metabolism
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