Polo-like kinase 1 (PLK1) induces Vemurafenib resistance in melanoma.

Polo-like kinase 1 (PLK1) induces Vemurafenib resistance in melanoma.

<p><b>(A)</b> Relative cell viability under the treatment of Vemurafenib in mouse melanoma cells (mMC) and mouse melanoma with Plk1 knock-in (mMPI) cells. <i>n</i> = 3 biological replicates. Mean ± SD. n.s., <i>P</i> > 0.05; * <i>P</i> < 0....

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書誌詳細
第一著者:	Fengyi Mao (15073242) (author)
その他の著者:	Sai Wu (6096290) (author), Derek B. Allison (15141675) (author), Daheng He (9189701) (author), Yifan Kong (4458616) (author), Chaohao Li (15141681) (author), Zhiguo Li (431917) (author), Yanquan Zhang (14930570) (author), Xinyi Wang (559030) (author), Qiongsi Zhang (2818111) (author), Chi Wang (131921) (author), Xiaoqi Liu (45630) (author)
出版事項:	2025
主題:	Cell Biology Genetics Molecular Biology Developmental Biology Cancer Hematology Biological Sciences not elsewhere classified suppress tumor growth like kinase 1 crucial transcription factor cnc homolog 1 clinical database analysis shortened mice survival >< sup >< div >< p cutaneous melanoma based v600e </ sup patient survival pten </ ca </ ></ sup synergistic efficiency novel function negatively correlates genes involved cell cycle cancer progression cancer metabolism bach1 ), >- deficiency
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