CMG2 receptor-dependent <i>in vivo</i> toxicity of anthrax edema toxin.
<p><b>A</b>. CMG2-KO mice and their littermate WT control mice were challenged with 20 µg ET (I.P.), and monitored for signs of malaise and survival for 200 hours. Log-rank test for survival comparison. <b>B</b>. ET-induced cAMP increases in mice. Eighteen hours after c...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2025
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
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| الملخص: | <p><b>A</b>. CMG2-KO mice and their littermate WT control mice were challenged with 20 µg ET (I.P.), and monitored for signs of malaise and survival for 200 hours. Log-rank test for survival comparison. <b>B</b>. ET-induced cAMP increases in mice. Eighteen hours after challenge with 30 µg ET (I.V.), the mice (CMG2-KO and the controls) were euthanized, and blood, liver, heart, kidneys were collected and processed for measuring cAMP levels. Unpaired two-tailed Student’s <i>t</i>-test.</p> |
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