Controls for NU7441 inhibitor of DNA-PKcs.

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Changkun Hu (12077989) (author)
مؤلفون آخرون:	Taylor Bugbee (12077992) (author), Dalton Dacus (12077995) (author), Rachel Palinski (12077998) (author), Nicholas Wallace (12078001) (author)
منشور في:	2022
الموضوعات:	Biophysics Biochemistry Genetics Molecular Biology Developmental Biology Cancer Hematology Infectious Diseases Biological Sciences not elsewhere classified Physical Sciences not elsewhere classified lesion could lead flow cytometry experiments double strand breaks make dna damage deleterious dna lesion homologous end joining specific chemical inhibitors destabilizing p300 demonstrates nhej occurs primarily 8e6 causes colocalization dna replication dna repair activated dna homologous templates homologous recombination hr occurs typically repaired repair pathways readily completed nhej factor nhej ). mimicking 8e6 induced dysregulation induced dsb immunofluorescence microscopy free system free manner fold increase better define 8e6 mutant 8e6 caused 200kb surrounding
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