High-Throughput Proteomics Reveals a Novel Small Open Reading Frame-Encoded Peptide That Promotes Hepatocellular Carcinoma Invasion and Migration

Long noncoding RNAs (lncRNAs) are closely associated with tumor development, and increasing evidence suggests that small open reading frame (smORF) within lncRNAs also have the capability to encode smORF-encoded peptides (SEPs). Here, we thoroughly uncovered the SEP expression profile of hepatocellu...

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Bibliographic Details
Main Author:	Fei Wang (19534) (author)
Other Authors:	En Hu (9342620) (author), Juping Li (20483678) (author), Jiahe Ouyang (17989165) (author), Xiaolong Liu (265696) (author), Xiaohua Xing (1392454) (author)
Published:	2024
Subjects:	Biochemistry Genetics Molecular Biology Cancer Biological Sciences not elsewhere classified throughput proteomics reveals throughput mass spectrometry sep expression profile increasing evidence suggests coding region proteins adjacent nontumor tissues overexpression significantly enhances ci ]: 1 01 – 1 within lncrnas also hcc tissues (< significantly upregulated thoroughly uncovered stability compared significant difference seps ). protein levels peptide encoded p </ hepatocellular carcinoma hcc cells findings highlight endogenous peptide encoded peptides encoded peptide could serve closely associated based methods 7 ]). 208 seps
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High-Throughput Proteomics Reveals a Novel Small Open Reading Frame-Encoded Peptide That Promotes Hepatocellular Carcinoma Invasion and Migration

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