Critical Role of Transcription Factor CtSR in Mediating Ergosterol Biosynthesis and DMI Fungicides Sensitivity in Colletotrichum truncatum

Anthracnose caused by Colletotrichum truncatum severely impacts global fruit/vegetable yields. Unlike other Colletotrichum species, C. truncatum exhibits inherent resistance to some sterol demethylation inhibitors (DMIs), necessitating an understanding of ergosterol synthesis regulation and resistan...

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Main Author:	Wei Sun (93580) (author)
Other Authors:	Yongqi He (7328414) (author), Huizhu Yuan (465108) (author), Tengyu Lei (21211564) (author), Xiaojing Yan (223994) (author), Daibin Yang (465106) (author), Shuning Chen (5876063) (author)
Published:	2025
Subjects:	Biochemistry Microbiology Cell Biology Genetics Molecular Biology Cancer Science Policy Infectious Diseases Plant Biology Virology Computational Biology Biological Sciences not elsewhere classified strain highly sensitive sterol demethylation inhibitors significant practical implications reduced mycelial growth hybrid assays confirmed ctsr directly binds mediating ergosterol biosynthesis ergosterol synthesis regulation dmis ), necessitating transcription factor ctsr dmi fungicides sensitivity ergosterol biosynthesis transcription factor ctru02_06681 ), dmi sensitivity dmi interactions ctsr </ abolished dmi yeast one wild type vegetable yields transcriptomic analysis taken together resistance mechanisms oxidative stress osmotic stress induced expression expression compared cyp51s </ critical role colletotrichum species
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Critical Role of Transcription Factor CtSR in Mediating Ergosterol Biosynthesis and DMI Fungicides Sensitivity in Colletotrichum truncatum

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