Flow diagram of the conversion of drugs into active substances.

<p>Flow diagram of the conversion of drugs into active substances.</p>

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Glavni avtor: Uğur Ejder (22683228) (author)
Drugi avtorji: Pınar Uskaner Hepsağ (22683231) (author)
Izdano: 2025
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author Uğur Ejder (22683228)
author2 Pınar Uskaner Hepsağ (22683231)
author2_role author
author_facet Uğur Ejder (22683228)
Pınar Uskaner Hepsağ (22683231)
author_role author
dc.creator.none.fl_str_mv Uğur Ejder (22683228)
Pınar Uskaner Hepsağ (22683231)
dc.date.none.fl_str_mv 2025-11-25T18:23:55Z
dc.identifier.none.fl_str_mv 10.1371/journal.pone.0336846.g001
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Flow_diagram_of_the_conversion_of_drugs_into_active_substances_/30713253
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biotechnology
Ecology
Cancer
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Information Systems not elsewhere classified
small sample size
lr &# 8211
evaluated using 5
assisted reproductive technologies
artificial bee colony
art ), yet
address class imbalance
support vector machine
pharmaceutical supplement use
enhance predictive performance
abc hybrids outperformed
abc hybrid counterparts
local interpretable model
abc hybrid model
model performance
supplement variables
producing interpretable
dietician support
vitro fertilization
synthetic minority
studies rely
sampling technique
retrospective dataset
regression tree
random forest
observed improvements
nearest neighbors
limited optimization
influential features
individual predictions
improving prediction
implemented alongside
future studies
four algorithms
folic acid
fold cross
exploratory rather
dietary data
conventional algorithms
concept study
clinically directive
binary representation
baseline models
algorithm models
agnostic explanations
accuracy ).
21 predictors
dc.title.none.fl_str_mv Flow diagram of the conversion of drugs into active substances.
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>Flow diagram of the conversion of drugs into active substances.</p>
eu_rights_str_mv openAccess
id Manara_bdbb0687e4b9011f4530059b27141ccd
identifier_str_mv 10.1371/journal.pone.0336846.g001
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30713253
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Flow diagram of the conversion of drugs into active substances.Uğur Ejder (22683228)Pınar Uskaner Hepsağ (22683231)BiotechnologyEcologyCancerBiological Sciences not elsewhere classifiedMathematical Sciences not elsewhere classifiedInformation Systems not elsewhere classifiedsmall sample sizelr &# 8211evaluated using 5assisted reproductive technologiesartificial bee colonyart ), yetaddress class imbalancesupport vector machinepharmaceutical supplement useenhance predictive performanceabc hybrids outperformedabc hybrid counterpartslocal interpretable modelabc hybrid modelmodel performancesupplement variablesproducing interpretabledietician supportvitro fertilizationsynthetic minoritystudies relysampling techniqueretrospective datasetregression treerandom forestobserved improvementsnearest neighborslimited optimizationinfluential featuresindividual predictionsimproving predictionimplemented alongsidefuture studiesfour algorithmsfolic acidfold crossexploratory ratherdietary dataconventional algorithmsconcept studyclinically directivebinary representationbaseline modelsalgorithm modelsagnostic explanationsaccuracy ).21 predictors<p>Flow diagram of the conversion of drugs into active substances.</p>2025-11-25T18:23:55ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0336846.g001https://figshare.com/articles/figure/Flow_diagram_of_the_conversion_of_drugs_into_active_substances_/30713253CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307132532025-11-25T18:23:55Z
spellingShingle Flow diagram of the conversion of drugs into active substances.
Uğur Ejder (22683228)
Biotechnology
Ecology
Cancer
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Information Systems not elsewhere classified
small sample size
lr &# 8211
evaluated using 5
assisted reproductive technologies
artificial bee colony
art ), yet
address class imbalance
support vector machine
pharmaceutical supplement use
enhance predictive performance
abc hybrids outperformed
abc hybrid counterparts
local interpretable model
abc hybrid model
model performance
supplement variables
producing interpretable
dietician support
vitro fertilization
synthetic minority
studies rely
sampling technique
retrospective dataset
regression tree
random forest
observed improvements
nearest neighbors
limited optimization
influential features
individual predictions
improving prediction
implemented alongside
future studies
four algorithms
folic acid
fold cross
exploratory rather
dietary data
conventional algorithms
concept study
clinically directive
binary representation
baseline models
algorithm models
agnostic explanations
accuracy ).
21 predictors
status_str publishedVersion
title Flow diagram of the conversion of drugs into active substances.
title_full Flow diagram of the conversion of drugs into active substances.
title_fullStr Flow diagram of the conversion of drugs into active substances.
title_full_unstemmed Flow diagram of the conversion of drugs into active substances.
title_short Flow diagram of the conversion of drugs into active substances.
title_sort Flow diagram of the conversion of drugs into active substances.
topic Biotechnology
Ecology
Cancer
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Information Systems not elsewhere classified
small sample size
lr &# 8211
evaluated using 5
assisted reproductive technologies
artificial bee colony
art ), yet
address class imbalance
support vector machine
pharmaceutical supplement use
enhance predictive performance
abc hybrids outperformed
abc hybrid counterparts
local interpretable model
abc hybrid model
model performance
supplement variables
producing interpretable
dietician support
vitro fertilization
synthetic minority
studies rely
sampling technique
retrospective dataset
regression tree
random forest
observed improvements
nearest neighbors
limited optimization
influential features
individual predictions
improving prediction
implemented alongside
future studies
four algorithms
folic acid
fold cross
exploratory rather
dietary data
conventional algorithms
concept study
clinically directive
binary representation
baseline models
algorithm models
agnostic explanations
accuracy ).
21 predictors