Noninvasive Diagnosis of Early-Stage Chronic Kidney Disease and Monitoring of the Hemodialysis Process in Clinical Practice via Exhaled Breath Analysis Using an Ultrasensitive Flexible NH<sub>3</sub> Sensor Assisted by Pattern Recognition

To achieve the early diagnosis of chronic kidney disease (CKD), noninvasive hemodialysis monitoring, and accurate determination of dialysis duration and adequacy, a noninvasive, point-of-care, user-friendly device should be developed. Here, a flexible, room temperature NH<sub>3</sub> gas...

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Main Author:	Xin Zhao (71840) (author)
Other Authors:	Xiaoyu You (19370438) (author), Zhenzhen Wang (250368) (author), Yanjie Liu (607219) (author), Huaian Fu (19370441) (author), Ge Li (65539) (author), Wenxiang Zheng (12091470) (author), Shanshan Yu (317797) (author), Zhipeng Tang (1937923) (author), Kai Zhang (102844) (author), Fei Song (86233) (author), Jie Zhao (49409) (author), Jinshun Wang (20933517) (author), Yuhao Pang (20306449) (author), Chen Yang (207381) (author), Qiuxia Li (534851) (author), Lixin Zhang (55947) (author), Hongbo Ma (6247616) (author), Xiaodong Zhao (327921) (author), Xinxin Xiang (446161) (author), Yanzhang Hao (20393292) (author), Qiang Jing (4234270) (author), Yaning Wang (2997282) (author), Bo Liu (127343) (author)
Published:	2025
Subjects:	Medicine Microbiology Neuroscience Chemical Sciences not elsewhere classified Physical Sciences not elsewhere classified Information Systems not elsewhere classified traditional blood tests strong positive correlation renal function evaluation receiver operating characteristic moderate positive correlation daily health status chronic kidney disease 48 healthy controls room temperature nh key breath biomarkers sensor could serve gas sensor sensitive ultrasensitive flexible nh pattern recognition algorithm 3 </ sub 39 ckd patients ckd  nh stage ckd patients pattern recognition stage ckd ckd biomarkers svm algorithm r </ ckd patients ckd samples ckd diagnosis sensor ’ sensor assisted used due results suggest hemodialysis processes hemodialysis process good results friendly device dialysis schedule dialysis process dialysis duration detection limits creatinine  constructed using clinical practice accurate determination 62 ), 100 ppb 1 ppm
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Noninvasive Diagnosis of Early-Stage Chronic Kidney Disease and Monitoring of the Hemodialysis Process in Clinical Practice via Exhaled Breath Analysis Using an Ultrasensitive Flexible NH<sub>3</sub> Sensor Assisted by Pattern Recognition

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