LAI-1-dependent LCV remodeling requires GBP.

LAI-1-dependent LCV remodeling requires GBP.

<p>(<b>A-C</b>) Dually labeled <i>D. discoideum</i> Ax2 or Δ<i>gnbp</i> producing calnexin (CnxA)-GFP (pAW016) and P4C-mCherry (pWS032) was treated with LAI-1 (10 µM, 1 h), or DMSO (solvent control), infected (MOI 5, 4 h) with mCerulean-producing <i>L....

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Bibliographic Details
Main Author:	Franziska Solger (8826224) (author)
Other Authors:	Jonas Rauch (21213524) (author), Simone Vormittag (17325505) (author), Mingzhen Fan (12403234) (author), Lyudmil Raykov (21213527) (author), Paul Charki (18513863) (author), Ana Katic (11137077) (author), François Letourneur (21213530) (author), Thierry Soldati (79025) (author), Jürgen Seibel (2742718) (author), Hubert Hilbi (72826) (author)
Published:	2025
Subjects:	Biochemistry Cell Biology Genetics Molecular Biology Ecology Developmental Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified vacuoles harboring avirulent resistant environmental bacterium lipid droplet markers legionnaires ’ disease div >< p efficient intracellular replication lcv markers calnexin hydroxyketone compound lai 1 derivatives inhibit dictyostelium discoideum </ legionella pneumophila </ kingdom signaling involves kingdom signaling pneumophila </ legionella </ discoideum </ intracellular growth gnbp </ 1 involves work shows taken together synthetic lai single guanylate replicates intracellularly mutually dependent mcs ). mammalian cells lcv localization lcv ). large gtpases distinct compartment dependent manner dependent inhibition causative agent binding protein antimicrobial factor 1 colocalizes 1 (<
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