$X-ray diffraction data and refinement statistics.$

X-ray diffraction data and refinement statistics.

<div><p>Unraveling the metabolism of <i>Treponema pallidum</i> is a key component to understanding the pathogenesis of the human disease that it causes, syphilis. For decades, it was assumed that glucose was the sole carbon/energy source for this parasitic spirochete. But the...

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Bibliographic Details
Main Author:	Ranjit K. Deka (15626723) (author)
Other Authors:	Shih-Chia Tso (3704401) (author), Wei Z. Liu (3044511) (author), Chad A. Brautigam (242609) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Microbiology Genetics Molecular Biology Evolutionary Biology Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified related treponemal species microaerophilic host environments cycle enzymes suggested alternative sources could evidence strongly supported treponema vincentii </ biochemical evidence supports second crystal structure named tp0476 ), div >< p acid sequence identity known acetate kinases alternative energy source treponema pallidum </ 3 å resolution biochemical evidence crystal structure energy source acetate kinases pallidum </ 36 å acetogenic energy acetate kinase sole carbon similar fold recent bioinformatic provided insight parasitic spirochete ostensibly catalyzes oral pathogen key component human disease homologous enzyme final enzyme enzyme ’ enzyme exists enzymatic activity
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X-ray diffraction data and refinement statistics.

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