Figure 3 from Extrachromosomal DNA–Driven Oncogene Spatial Heterogeneity and Evolution in Glioblastoma

Figure 3 from Extrachromosomal DNA–Driven Oncogene Spatial Heterogeneity and Evolution in Glioblastoma

<p>SPECIES spatial modeling of ecDNA evolution. <b>A</b> and <b>B,</b> DNA FISH staining of two representative GBM samples from the GB-UK cohort, revealing (<b>A</b>) <i>EGFR</i>- and (<b>B</b>) <i>PDGFRA</i>-ecDNA. <i&...

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Main Author: Imran Noorani (9184605) (author)
Other Authors: Magnus Haughey (22375292) (author), Jens Luebeck (15040173) (author), Andrew Rowan (15489418) (author), Eva Grönroos (15117034) (author), Francesco Terenzi (22375295) (author), Ivy Tsz-Lo Wong (20549683) (author), Davide Pradella (22375298) (author), Marta Lisi (22375301) (author), Jeanette Kittel (22375304) (author), Natasha Sharma (22375307) (author), Chris Bailey (22375310) (author), Clare E. Weeden (15295843) (author), Donald M. Bell (22375313) (author), Eric Joo (22375316) (author), Vittorio Barbè (22375319) (author), Matthew G. Jones (20549692) (author), King L. Hung (15117769) (author), Emma L. Nye (15489571) (author), Mary Green (18717219) (author), Lucy Meader (22375322) (author), Emma J. Norton (22375325) (author), Mark Fabian (22375328) (author), Nnennaya Kanu (22375331) (author), Mariam Jamal-Hanjani (15386766) (author), Thomas Santarius (22375334) (author), Andrea Ventura (22375337) (author), James A.R. Nicoll (22375340) (author), Delphine Boche (21902885) (author), Howard Y. Chang (20549704) (author), Vineet Bafna (15040200) (author), Weini Huang (17379552) (author), Paul S. Mischel (15040185) (author), Charles Swanton (14123052) (author), Benjamin Werner (22375343) (author)
Published: 2025
Subjects:
Cancer
Tumor Biology
Methods and Technology
Cancer Prevention
Cancer Interception
Biomarkers and intervention
Computational Methods
Mathematical modeling
Tumor Evolution
Tumor Heterogeneity
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