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<div><p>Hydrated electrons (e<sub>aq</sub><sup>-</sup>) are widely studied in pollutant degradation owing to their high reducing power. Recent studies indicate that transiently generated e<sub>aq</sub><sup>-</sup> during radiotherapy can en...

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Autore principale: Zhuangbin Zheng (22676304) (author)
Altri autori: Fanlei Ran (7352957) (author), Lushan Liang (22676307) (author), Yiqian Zhang (752795) (author), Xianwen Li (3910537) (author), Liqun Zhang (115900) (author), Lijun Bi (121470) (author)
Pubblicazione: 2025
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Riassunto:<div><p>Hydrated electrons (e<sub>aq</sub><sup>-</sup>) are widely studied in pollutant degradation owing to their high reducing power. Recent studies indicate that transiently generated e<sub>aq</sub><sup>-</sup> during radiotherapy can enhance chemotherapeutic antitumor effects via reduction activity. However, biomedical applications remain limited because conventional methods generate e<sub>aq</sub><sup>-</sup> in situ and are short-lived, precluding storage. In this study, we present a storable electromagnetic base liquid (EBL), reference-linked to prior preparation work, and analyze its physicochemical and organism-level effects. The EBL showed strong alkalinity (pH 13.08), low oxidation-reduction potential (ORP 47.1 mV), and a total antioxidant capacity of 1.6 mM Trolox equivalents antioxidant capacity. Using a larva zebrafish (<i>Danio rerio</i>) digital phenotyping platform, we identified a non-adverse concentration and generated unbiased predictions clustering EBL with antitumor, uric acid-lowering, and hypoglycemic drugs. These findings motivate further biological investigation of EBL’s biomedical potential and provide a basis for subsequent validation.</p></div>