Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

<p>Integrated gene set enrichment analysis by body mass index (BMI) with correction for S phase. This figure presents a dotplot of genes differentially up- or downregulated in OW/OB patients versus NL BMI patients. Red indicates upregulation in OW/OB verse NL. The far left column is all patien...

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Автор:	Andrew W. Hahn (15024693) (author)
Інші автори:	Ashley V. Menk (15049194) (author), Dayana B. Rivadeneira (15049197) (author), Ryan C. Augustin (15049200) (author), Mingchu Xu (15049203) (author), Jun Li (15049206) (author), Xiaogang Wu (15049209) (author), Aditya K. Mishra (15049212) (author), Tuba N. Gide (15049215) (author), Camelia Quek (15049218) (author), Yan Zang (15049221) (author), Christine N. Spencer (15049224) (author), Alexander M. Menzies (11420816) (author), Carrie R. Daniel (15049227) (author), Courtney W. Hudgens (15049230) (author), Theodore Nowicki (15049233) (author), Lauren E. Haydu (15049236) (author), M.A. Wadud Khan (15049239) (author), Vancheswaran Gopalakrishnan (15049242) (author), Elizabeth M. Burton (15049245) (author), Jared Malke (15049248) (author), Julie M. Simon (15049251) (author), Chantale Bernatchez (15030624) (author), Nagireddy Putluri (15049254) (author), Scott E. Woodman (15049257) (author), Y.N. Vashisht Gopal (15049260) (author), Renato Guerrieri (15049263) (author), Grant M. Fischer (15049266) (author), Jian Wang (15049269) (author), Khalida M. Wani (15049272) (author), John F. Thompson (13716714) (author), Jeffrey E. Lee (15049275) (author), Patrick Hwu (15049278) (author), Nadim Ajami (15049281) (author), Jeffrey E. Gershenwald (15049284) (author), Georgina V. Long (11420813) (author), Richard A. Scolyer (10778711) (author), Michael T. Tetzlaff (15049287) (author), Alexander J. Lazar (14963562) (author), Dirk Schadendorf (14850769) (author), Jennifer A. Wargo (15049290) (author), John M. Kirkwood (15023483) (author), Ralph J. DeBerardinis (15049293) (author), Han Liang (15049296) (author), Andrew Futreal (14855103) (author), Jianhua Zhang (15049299) (author), James S. Wilmott (15008931) (author), Weiyi Peng (15014165) (author), Michael A. Davies (14932995) (author), Greg M. Delgoffe (15049302) (author), Yana G. Najjar (15049305) (author), Jennifer L. McQuade (15008940) (author)
Опубліковано:	2025
Предмети:	Cancer Cancer Risk Factors Molecular and Cellular Biology Therapeutic Research and Development Endogenous Risk Factors Obesity Metabolism Metabolomics Skin Cancers Melanoma Translational Research
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author	Andrew W. Hahn (15024693)
author2	Ashley V. Menk (15049194) Dayana B. Rivadeneira (15049197) Ryan C. Augustin (15049200) Mingchu Xu (15049203) Jun Li (15049206) Xiaogang Wu (15049209) Aditya K. Mishra (15049212) Tuba N. Gide (15049215) Camelia Quek (15049218) Yan Zang (15049221) Christine N. Spencer (15049224) Alexander M. Menzies (11420816) Carrie R. Daniel (15049227) Courtney W. Hudgens (15049230) Theodore Nowicki (15049233) Lauren E. Haydu (15049236) M.A. Wadud Khan (15049239) Vancheswaran Gopalakrishnan (15049242) Elizabeth M. Burton (15049245) Jared Malke (15049248) Julie M. Simon (15049251) Chantale Bernatchez (15030624) Nagireddy Putluri (15049254) Scott E. Woodman (15049257) Y.N. Vashisht Gopal (15049260) Renato Guerrieri (15049263) Grant M. Fischer (15049266) Jian Wang (15049269) Khalida M. Wani (15049272) John F. Thompson (13716714) Jeffrey E. Lee (15049275) Patrick Hwu (15049278) Nadim Ajami (15049281) Jeffrey E. Gershenwald (15049284) Georgina V. Long (11420813) Richard A. Scolyer (10778711) Michael T. Tetzlaff (15049287) Alexander J. Lazar (14963562) Dirk Schadendorf (14850769) Jennifer A. Wargo (15049290) John M. Kirkwood (15023483) Ralph J. DeBerardinis (15049293) Han Liang (15049296) Andrew Futreal (14855103) Jianhua Zhang (15049299) James S. Wilmott (15008931) Weiyi Peng (15014165) Michael A. Davies (14932995) Greg M. Delgoffe (15049302) Yana G. Najjar (15049305) Jennifer L. McQuade (15008940)
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author
author_facet	Andrew W. Hahn (15024693) Ashley V. Menk (15049194) Dayana B. Rivadeneira (15049197) Ryan C. Augustin (15049200) Mingchu Xu (15049203) Jun Li (15049206) Xiaogang Wu (15049209) Aditya K. Mishra (15049212) Tuba N. Gide (15049215) Camelia Quek (15049218) Yan Zang (15049221) Christine N. Spencer (15049224) Alexander M. Menzies (11420816) Carrie R. Daniel (15049227) Courtney W. Hudgens (15049230) Theodore Nowicki (15049233) Lauren E. Haydu (15049236) M.A. Wadud Khan (15049239) Vancheswaran Gopalakrishnan (15049242) Elizabeth M. Burton (15049245) Jared Malke (15049248) Julie M. Simon (15049251) Chantale Bernatchez (15030624) Nagireddy Putluri (15049254) Scott E. Woodman (15049257) Y.N. Vashisht Gopal (15049260) Renato Guerrieri (15049263) Grant M. Fischer (15049266) Jian Wang (15049269) Khalida M. Wani (15049272) John F. Thompson (13716714) Jeffrey E. Lee (15049275) Patrick Hwu (15049278) Nadim Ajami (15049281) Jeffrey E. Gershenwald (15049284) Georgina V. Long (11420813) Richard A. Scolyer (10778711) Michael T. Tetzlaff (15049287) Alexander J. Lazar (14963562) Dirk Schadendorf (14850769) Jennifer A. Wargo (15049290) John M. Kirkwood (15023483) Ralph J. DeBerardinis (15049293) Han Liang (15049296) Andrew Futreal (14855103) Jianhua Zhang (15049299) James S. Wilmott (15008931) Weiyi Peng (15014165) Michael A. Davies (14932995) Greg M. Delgoffe (15049302) Yana G. Najjar (15049305) Jennifer L. McQuade (15008940)
author_role	author
dc.creator.none.fl_str_mv	Andrew W. Hahn (15024693) Ashley V. Menk (15049194) Dayana B. Rivadeneira (15049197) Ryan C. Augustin (15049200) Mingchu Xu (15049203) Jun Li (15049206) Xiaogang Wu (15049209) Aditya K. Mishra (15049212) Tuba N. Gide (15049215) Camelia Quek (15049218) Yan Zang (15049221) Christine N. Spencer (15049224) Alexander M. Menzies (11420816) Carrie R. Daniel (15049227) Courtney W. Hudgens (15049230) Theodore Nowicki (15049233) Lauren E. Haydu (15049236) M.A. Wadud Khan (15049239) Vancheswaran Gopalakrishnan (15049242) Elizabeth M. Burton (15049245) Jared Malke (15049248) Julie M. Simon (15049251) Chantale Bernatchez (15030624) Nagireddy Putluri (15049254) Scott E. Woodman (15049257) Y.N. Vashisht Gopal (15049260) Renato Guerrieri (15049263) Grant M. Fischer (15049266) Jian Wang (15049269) Khalida M. Wani (15049272) John F. Thompson (13716714) Jeffrey E. Lee (15049275) Patrick Hwu (15049278) Nadim Ajami (15049281) Jeffrey E. Gershenwald (15049284) Georgina V. Long (11420813) Richard A. Scolyer (10778711) Michael T. Tetzlaff (15049287) Alexander J. Lazar (14963562) Dirk Schadendorf (14850769) Jennifer A. Wargo (15049290) John M. Kirkwood (15023483) Ralph J. DeBerardinis (15049293) Han Liang (15049296) Andrew Futreal (14855103) Jianhua Zhang (15049299) James S. Wilmott (15008931) Weiyi Peng (15014165) Michael A. Davies (14932995) Greg M. Delgoffe (15049302) Yana G. Najjar (15049305) Jennifer L. McQuade (15008940)
dc.date.none.fl_str_mv	2025-11-25T12:43:50Z
dc.identifier.none.fl_str_mv	10.1158/1078-0432.30705984
dc.relation.none.fl_str_mv	https://figshare.com/articles/figure/Supplementary_Figure_S1_from_Obesity_Is_Associated_with_Altered_Tumor_Metabolism_in_Metastatic_Melanoma/30705984
dc.rights.none.fl_str_mv	CC BY info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv	Cancer Cancer Risk Factors Molecular and Cellular Biology Therapeutic Research and Development Endogenous Risk Factors Obesity Metabolism Metabolomics Skin Cancers Melanoma Translational Research
dc.title.none.fl_str_mv	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
dc.type.none.fl_str_mv	Image Figure info:eu-repo/semantics/publishedVersion image
description	<p>Integrated gene set enrichment analysis by body mass index (BMI) with correction for S phase. This figure presents a dotplot of genes differentially up- or downregulated in OW/OB patients versus NL BMI patients. Red indicates upregulation in OW/OB verse NL. The far left column is all patients, and then, an analysis controlling for sex, cohort, and tissue site is shown in the 3 columns to the right.</p>
eu_rights_str_mv	openAccess
id	Manara_c26861aa3af38a63dfeaea8f3724497b
identifier_str_mv	10.1158/1078-0432.30705984
network_acronym_str	Manara
network_name_str	ManaraRepo
oai_identifier_str	oai:figshare.com:article/30705984
publishDate	2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv	CC BY
spelling	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic MelanomaAndrew W. Hahn (15024693)Ashley V. Menk (15049194)Dayana B. Rivadeneira (15049197)Ryan C. Augustin (15049200)Mingchu Xu (15049203)Jun Li (15049206)Xiaogang Wu (15049209)Aditya K. Mishra (15049212)Tuba N. Gide (15049215)Camelia Quek (15049218)Yan Zang (15049221)Christine N. Spencer (15049224)Alexander M. Menzies (11420816)Carrie R. Daniel (15049227)Courtney W. Hudgens (15049230)Theodore Nowicki (15049233)Lauren E. Haydu (15049236)M.A. Wadud Khan (15049239)Vancheswaran Gopalakrishnan (15049242)Elizabeth M. Burton (15049245)Jared Malke (15049248)Julie M. Simon (15049251)Chantale Bernatchez (15030624)Nagireddy Putluri (15049254)Scott E. Woodman (15049257)Y.N. Vashisht Gopal (15049260)Renato Guerrieri (15049263)Grant M. Fischer (15049266)Jian Wang (15049269)Khalida M. Wani (15049272)John F. Thompson (13716714)Jeffrey E. Lee (15049275)Patrick Hwu (15049278)Nadim Ajami (15049281)Jeffrey E. Gershenwald (15049284)Georgina V. Long (11420813)Richard A. Scolyer (10778711)Michael T. Tetzlaff (15049287)Alexander J. Lazar (14963562)Dirk Schadendorf (14850769)Jennifer A. Wargo (15049290)John M. Kirkwood (15023483)Ralph J. DeBerardinis (15049293)Han Liang (15049296)Andrew Futreal (14855103)Jianhua Zhang (15049299)James S. Wilmott (15008931)Weiyi Peng (15014165)Michael A. Davies (14932995)Greg M. Delgoffe (15049302)Yana G. Najjar (15049305)Jennifer L. McQuade (15008940)CancerCancer Risk FactorsMolecular and Cellular BiologyTherapeutic Research and DevelopmentEndogenous Risk FactorsObesityMetabolismMetabolomicsSkin CancersMelanomaTranslational Research<p>Integrated gene set enrichment analysis by body mass index (BMI) with correction for S phase. This figure presents a dotplot of genes differentially up- or downregulated in OW/OB patients versus NL BMI patients. Red indicates upregulation in OW/OB verse NL. The far left column is all patients, and then, an analysis controlling for sex, cohort, and tissue site is shown in the 3 columns to the right.</p>2025-11-25T12:43:50ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30705984https://figshare.com/articles/figure/Supplementary_Figure_S1_from_Obesity_Is_Associated_with_Altered_Tumor_Metabolism_in_Metastatic_Melanoma/30705984CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307059842025-11-25T12:43:50Z
spellingShingle	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma Andrew W. Hahn (15024693) Cancer Cancer Risk Factors Molecular and Cellular Biology Therapeutic Research and Development Endogenous Risk Factors Obesity Metabolism Metabolomics Skin Cancers Melanoma Translational Research
status_str	publishedVersion
title	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
title_full	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
title_fullStr	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
title_full_unstemmed	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
title_short	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
title_sort	Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
topic	Cancer Cancer Risk Factors Molecular and Cellular Biology Therapeutic Research and Development Endogenous Risk Factors Obesity Metabolism Metabolomics Skin Cancers Melanoma Translational Research

Supplementary Figure S1 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

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