Lipidomics Facilitates the Discovery of Diagnostic Biomarkers in Patients with Chronic Total Occlusion during the Perioperative Period

Lipidomics Facilitates the Discovery of Diagnostic Biomarkers in Patients with Chronic Total Occlusion during the Perioperative Period

Chronic total occlusion (CTO) is a subtype of cardiovascular disease associated with high mortality and an increased risk of ventricular arrhythmia. This study aimed to investigate lipidomic changes in CTO patients undergoing percutaneous coronary intervention (PCI) using a tandem-lipidomic strategy...

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Bibliographic Details
Main Author: Zhenxin Wang (730316) (author)
Other Authors: Xin Zhong (464533) (author), Kaidi Wang (205522) (author), Lei Zhang (38117) (author), Hua Li (46469) (author), Yingfei Peng (21482617) (author), Fangjun Chen (6296003) (author), Wei Guo (86150) (author), Pengyuan Yang (135243) (author), Quanqing Zhang (1699543) (author), Huali Shen (624840) (author), Ling Lin (57361) (author)
Published: 2025
Subjects:
Medicine
Cell Biology
Physiology
Sociology
Immunology
Space Science
Mathematical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
predicting surgical outcomes
multiple reaction monitoring
monitoring postoperative prognosis
chronic total occlusion
cardiovascular disease associated
targeted lipidomic analysis
investigate lipidomic changes
global lipidomic approach
distinguishing cto patients
lipidomic strategy
ventricular arrhythmia
successfully separating
successfully quantified
study aimed
serum lipidomes
quantification method
potential biomarker
perioperative period
lipidomics facilitates
lipid profile
increased risk
first applied
finding suggests
diagnostic biomarkers
control donors
conditional biomarker
613 lipids
1500 lipids
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